γ-Gamma aminobutyric acid
Gamma aminobutyric acid (GABA) is a compound, also known as gamma aminobutyric acid, is a four carbon, non protein amino acid, widely exists in vertebrates, plants and microorganisms [1].
Aminobutyric acid refers to gamma aminobutyric acid, also known as aminobutyric acid. It is a kind of non protein amino acid widely existing in prokaryotes and eukaryotes in free state. It has a variety of functions in mammalian brain and spinal cord, and acts as an inhibitory neurotransmitter in the central nervous system. The reported physiological activities include regulating blood pressure, promoting mental stability, promoting cerebral blood flow, enhancing brain vitality, nourishing nerve cells, increasing growth hormone secretion, strengthening liver and kidney, preventing obesity, promoting alcohol metabolism (sobering up), improving menopausal syndrome and so on [2][3].
Published scientific studies have shown that GABA has the following functions in human body:
·Lower blood pressure [4] [5]
·Regulating arrhythmia [6]
·Regulating hormone secretion [7] [8]
·Brain function [9] [10]
·Asthma control [11]
Status:
Functions:
Mechanism:
·It plays an inhibitory role in thalamic cortical projection [14] [15] [16]
·Protect cells by scavenging free radicals and reducing lipid oxidation [17] [18]
Safety:
Safety is crucial for vulnerable groups (such as the elderly and infants). Oral toxicity tests and a large number of clinical studies have confirmed the safety of GABA, and no adverse reactions were found among the subjects. *GABA is safe and has been certified by FDA gras.
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[15].林华锦. 氨酪酸治疗婴幼儿夜间惊啼综合症20例疗效观察[J]. 肇庆医药, 1989, (1): 63-65.
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[17].Hou C W . Pu-Erh tea and GABA attenuates oxidative stress in kainic acid-induced status epilepticus[J]. Journal of Biomedical Science, 2011, 18(1):75.
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